IDSA's Secrets:

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PubMed: TLR2

"New World Disorder"
IDSA's Persistence "Cryme Disease" book Klempner's Fraud RICO Patents Osp-A/Viral Synergy Grants Search "TLR2" Kissinger NWO Beast
Relapsing Fever Dearborn Quotes Plum Island Corixa RICO "LYMErix ▲ Disease" Myco & Erythrocytes Rx Brain Damage
Steere Falsifies Test Dearborn Booklet Russians & NYMC CDCs Patents w/SKB GarthNicolson-GWI Rockefeller/Psychiatry
IDSA's Imitators Schoen-LYMErix IDSA: "Cyst Viable" DARPA Boots CDC Confronting Crooked NIH CT Med Board Hell/NDEs
IDSA's ShellGame Weinstein's Frauds LYMErix ►Imitators Auwaerter Epstein-Barr NIH Disinfo Foreign CPS' Sexual Assaults
IDSA's Biomarkers Yale's Valid Test UConn's KidTuskegee Plum Stupid Vaccines' Brain Damage Fraud With Intent   CPS' Entrapment
IDSA's Stupid Rx
 
Not used ▲to assess LYMErix? Yale's Congen Lyme
 
IDSA ▲ self-indicts
 

 
Update on Sex Abuse
 


24 May 2012 

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CDC writes a "bogus article" on Mycoplasma in the blood and Chronic Fatigue.
 

Lyme/LYMErix Cryme Reveals  New Paradigm in Health/Disease:
"Bacterial/Viral Coinfections";

TLR2 (fungi)Signaling Depletes IRAK1 and Inhibits Induction of Type 1 by TLR7/9  (viruses)-- 
-CV Harding, 2012  (More in the chart at the bottom of this homepage)

CFIDS = Seronegative Chronic Active EBV

"Multiple Mechanisms of Immune Suppression by B Lymphocytes" (New and Trashes Yale and IDSA)

NIH's Treatment Recommendations for Chronic Active Epstein-Borreliosis, the chronic illness also induced by OspA vaccination or exposure to molds.

The Antics of the Crazy Stalker Durland Fish and the New Genre in "Education."
 


CDC Greed (won't answer the FOIA)

ELISA = arbitrary cutoff.

Disclaimer

Overview


TUSKEGEE - By Jerry Leonard


1998, CIA Oilmen & Israelis plan to overthrow Saddam for the oil.

Bush/Gore  Oil/War-(Oct,2000)  

Bush's own explainer (Oct 2000) re: Iraq Oil




 

 




3 BILLION DOLLAR JP MORGAN LOSS BLAMED ON IDSOCIETY.org's FAMOUS NOT-ENOUGH-SEX DISEASE:

"As early as 2010, the senior banker who has been blamed for the debacle, Ina Drew, began to lose her grip on the bank’s chief investment office, ..."
"...But after contracting Lyme disease in 2010, she was frequently out of the office for a critical period, when her unit was making riskier bets, and her absences allowed long-simmering internal divisions and clashing egos to come to the fore, the traders said. "
 

www.nytimes.com
Discord in 2010 and 2011 contributed to the JPMorgan chief investment office’s giant losing trades in 2012, current and former bankers said.

"The Times and JPMorganChase report that Drew didn't get to IDSA soon enough to get her Rx of Viagra for her husband in order to head off the debacle."


So is there going to be a Lyme-Bailout or are the investors who lost the $3 billion going to sue Yale to recover the damages?
 

 

Mark Klempner performed the usual victim-blaming BS with a "checklist" instead of IDSA's biomarkers and IDSA's proper DNA-testing and the whole Mairkin Medical Establishment swooned instead of gagged.  

 

 

There are going to be even greater losses to come due to the fact that the NIH and CDC cannot admit what OspA or Lyme is.  The other news in the NYTimes has to do with Fauci and yet another HIV vaccine failure (see below for the link).
 

You'd be allowed to question whether or not these failures and delays are deliberate or are they all just plain stupid?  Or are they just plain stupid because as "bad Catholics," Fauci, Collins and Sebelius are allowed no Insight?

 

"the decline of thought and the weakening of the capacity of intelligence for what is real."



Vanity is the stem cells transplant that inhibits US.gov's medical competence. 
Vanity is the kernel, the cancer, the disease of the mind suffered by all USA's government employees.
Vanity is why the USA sucks at everything.
Vanity is the reason the USA produces no scholars.
 


BREAKING LYME CRYME NEWS:

YOU CAN TAKE THIS TO THE COURTS AND THE BANKS, PEEPS: HERE IS YOUR LAWSUIT:

The Role of TLR2 in Infection and Immunity

"TLR2 is also involved in NK cell response, as demonstrated by ***impaired NK cell activity and increased murine CMV load*** in TLR2 knockout mice (Szomolanyi-Tsuda et al., 2006)."
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342043/?tool=pubmed


It's an incomplete report, but it's a start, for sure.  See more about it here: Osp-A/Viral Synergy
 

ALSO NEW: 

IRAK-M modulates expression of IL-10 and cell surface markers CD80 and MHC II after bacterial re-stimulation of tolerized dendritic cells.

"
Along with endotoxin, bacterial sonicate is able to induce refractory tolerance in BM-DCs, and IRAK-M plays a role in modulating cell surface expression of MHC class II and CD80 and release of IL-10 during this tolerance." [Means: produces no antibodies]
http://www.ncbi.nlm.nih.gov/pubmed/22472665
 

Your lawsuit for misdiagnosis and damages is against Yale University, since they have owned the only scientifically valid early (and late) antibody test for Lyme since 1991: Yale's Valid TestBut they did not use this test to qualify LYMErix, because they knew LYMErix did not prevent "Lyme Disease."

IDSociety.org's and the CDC's entire "Lyme" paradigm is now officially discarded.

If you have been misdiagnosed because of the bogus ELISA/Dearborn protocol, this is the basis of your lawsuit.  LYMErix is the last thing that ever could have been a vaccine.  See, next, more about how we all have LYMErix-Disease due to spirochetal blebbing:


LYMErix-Disease helps us understand the epidemic of "Autism" from vaccines [1) vaccination of immunosuppressed kids causes the kids to suffer reactivated viruses from the vaccines, or 2) via immunosuppression by mycoplasmal (OspA-like) contamination of vaccines and subsequently reactivated viruses];

That is why what Lyme, OspA, and LYMErix disease is, is such a big secret that NIH Director Francis Collins last week threatened to have me arrested if I kept asking what OspA was (LOL).


OspA-like Blebs (see arrows in the below micrograph) are shed lipoproteins, so everyone with "Lyme disease," also has LYMErix Disease, because that is actually the disease - the chronic exposure to Borrelial OspA-like blebs resulting in immunosuppression, tolerance to mycoplasma in the blood (causes fatigue), results in no antibodies being produced, and the activation of Epstein-Barr/Similars.
 


http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=7103461


Or, as CDC officer and owner of the ImmuLyme OspA patent Alan Barbour says, we're exposed to/autovaccinated with OspA-like fungal blebs like flak:

"Or, using another diversionary tactic called blebbing, the spirochete can pinch off bits of its membrane in order to release its surface proteins. Explains Barbour: "It's like a bacterial Star Wars defense program," in which released surface proteins might intercept incoming host antibodies, keeping the spirochete safe from immunological attack. -- http://www.actionlyme.org/BARBOURS_STEALTH_BOMBERS.htm

 

 

120517 1:00 PM EST:   

Background:  FROM LYMERIX-DISEASE WE KNOW THAT:

Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1.
"Preculture of the cells with Pam(3)Cys [LYMErix or OspA Blebs, as shown above- KMD] at 1 microg/ml leads to a reduced response after subsequent stimulation with Pam(3)Cys at 10 microg/ml, indicating that the cells have become tolerant to Pam(3)Cys. The CD14 and TLR2 expression is not decreased on the surface of the tolerant cells, but rather up-regulated. Analysis of the NF-kappaB binding in Pam(3)Cys-tolerant cells shows a failure to mobilize NF-kappaB-p50p65 heterodimers, while NF-kappaB-p50p50 homodimers remain unchanged. Pam(3)Cys-tolerant cells showed neither IkappaBalpha-Ser(32) phosphorylation nor IkappaBalpha degradation but MyD88 protein was unaltered."  http://www.ncbi.nlm.nih.gov/pubmed/15294992 


Big Lyme Science News regarding the mechanisms by which OspA and Lyme spirochetes shedding OspA-like TLR-2 agonists (called blebs) activate Epstein-Barr/Similars:

SERONEGATIVE, ACTIVATED EPSTEIN-BARR, SIMILAR MECHANISMS OF INHIBITION OF NF-KAPPA ACTIVATION AS OSP-A:

http://www.ncbi.nlm.nih.gov/pubmed/21527913

LMP1 association with CD63 in endosomes and secretion... [EMBO J. 2011] - PubMed - NCBI

NF-Kappa
- that's a big one in the downstream mechanisms of immune inhibition and resultant inhibition of apoptosis of Lyme or OspA-like (mycoplasma) infected cells as a result of exposure to fungal antigens like OspA and the blebbing or shedding spirochetes in the Borrelia/Relapsing Fever group.  See more here 101016.htm on Epstein-OspA-Borreliosis.  (Search for nf-kappa in this page)

We can expect that Paul Auwaerter knows all about the mechanisms of immunosuppression related to funky fungal antigens because of this Johns Hopkins' Epstein-Barr investigator and his investigations of nf-kappa:
http://biolchem.bs.jhmi.edu/bcmb/Pages/faculty/faculty_detail.aspx?FID=140

 

See also:
 

CFIDS =  Seronegative EBV (4 reports)

Down-regulation of MHC class II expression through... [J Immunol. 2009] - PubMed - NCBI

 

The NIH, CDC, Yale and IDSA have no infectious diseases experts.  They suck as science because they're evil (see more about that below). You are are on your own.
 

But remember the logo: Blebbing is shedding of OspA and you are auto-vaccinated with Borrelial Blebs if you have Lyme or Chronic Lyme or Relapsing Fever or whatever we're calling it - today's onomatopoeia.

You are a Borrelial Blebbette or a Borrelial Blebboid.  You did not have to get the LYMErix vaccine to have the same disease the vaccine caused because you are being autovaccinated constantly by borrelial shedding of the little fat molecules of OspA (that the NIH refuses to identify) called blebs.

Your immune system is altered and now you are the host to all kinds of mycoplasma that make you fatigued and you are also a walking virus factory, not to mention a walking TB factory (you can't fight off TB, but that is a good thing because the next flu pandemic won't kill you).

 


And now back to the REtards, liars, fascists, terrorists, and assholes who "work" for the NIH and CDC:


"Bad Catholics": Anthony Fauci, Francis Collins, Kathleen Sebelius

THREATS, instead of answers, for sick people.

Keep reading...

 

"Top Scientist" Anthony Fauci does not know what OspA is, but then again, US News and World Report has become another Israeli Rag.  Oh, and by the way, Mort Zuckerman - owner of US News - is a sponsor of the Israeli criminal ALDF.com gang.

http://www.washingtonpost.com/wp-dyn/content/video/2009/02/12/VI2009021203091.html


Meanwhile, according to the famous plan of the NIH to hook up with BigPharma to market half-dead drugs, no one mentions the fact that Fauci owns a patent for the treatment of immune suppression outcomes of fungal infections or exposure to Osp-A:


  1. "Illustrative of specific disease states in treatment of which the present invention can be applied are HIV infection and other diseas...
    es characterized by a decrease of T-cell immunity, for example, mycobacterial infections like tuberculosis and fungal infections such as cryptococcal disease."






    http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5%2C696%2C079.PN.&OS=PN%2F5%2C696%2C079&RS=PN%2F5%2C696%2C079


    More on FAUCI THE FUMBLER:

    ‎"The initial empirical approach of immunizing with VaxGen's AIDSVax, a recombinant form of the outer glycoprotein-120 (gp120) portion of the HIV envelope, which was based on a strategy that was successful with hepatitis B, failed to protect volunteers from infection, apparently because the vaccine did not induce broadly neutralizing antibodies.3"  

    www.nejm.org

     

    More on FAUCI THE FUMBLER:

    1. 120518: NYTimes: Trial Vaccine Made Some More Vulnerable to H.I.V., Study Confirms

      http://www.nytimes.com/2012/05/18/health/research/trial-vaccine-made-some-more-vulnerable-to-hiv-study-confirms.html?_r=1&hpw
       
       

      Ya might say the NIH and CDC are "cursed," eh? 

      That would be because they won't come clean about Lyme and LYMErix.


       

      Confronting the Cowards Anthony Fauci and Francis Collins:

      To: esnyder@hbs.edu  (Harvard Business School Mormon featured in WaPo)
       
      Cc: sr393d@nih.gov, francis.collins@nih.gov, "Allen,Marin (NIH/OD) [E]" <AllenM1@mail.nih.gov>, zach_dann@blumenthal.senate.gov, francis.collins@nih.gov, "Strikas,Raymond A. (Ray) (CDC/OID/NCIRD)" <ras8@cdc.gov>, olib@od.nih.gov, afauci@niaid.nih.gov, joseph.breen@nih.gov, michael.greenwood@yale.edu, richard.horton@lancet.com, astrid.james@lancet.com, spinlyme@yahoogroups.com, roth@blackstone.com, spinlyme@yahoogroups.com, m.zecevic@lancet.com, ideditorial@lancet.com, Lawrence.Tabak@nih.gov, pgauwaerter@gmail.com

       
      Subject: Fearless WaPo Leader Anthony Fauci's Patent for Immunosuppression Outcomes like LYMErix Disease
       

       

      Date: May 17, 2012 6:16 AM

      Dear Sir (Harvard Business School's
      http://www.washingtonpost.com/national/on-leadership/if-harvard-business-school-were-a-religion-it-could-be-mormonism/2012/05/11/gIQA04biIU_story.html
      Clayton Christensen),

      Since your Harvard and Mormon expertise is
      in "asking the right questions," I ask you
      again to please ask Anthony Fauci if he
      could find out for the nation what OspA,
      the Lyme vaccines (ImmuLyme and LYMErix)
      is.

      Remember that Fauci said publically on CNN
      on the Lou Dobbs show that OspA was "scientifically
      a vaccine":

      http://edition.cnn.com/TRANSCRIPTS/0306/20/ldt.00.html

      "We've had an effective vaccine, but it's the kind of vaccine that you have to essentially vaccinate people each year. And from the standpoint of it's use, it has not been used as efficiently as it could have been used. So scientifically, we had a vaccine and still do have a vaccine, but it's not really well used." -- Anthony Fauci


      But no one at the NIH, CDC, IDSociety.org, or
      Yale has been able to answer my simple question
      as to what exactly OspA is/was/does.

      Now, a few years ago, Anthony Fauci was featured
      in WaPo and the US News and World Report (now owned
      by Mort Zuckerman who was a supporter of the criminal
      Lyme cryme gang, the ALDF.com - the non-non-profit
      who designed the disease, "Lyme" around the outcomes of
      OspA as a vaccine), credited as a "Leader" like yourself:
       
      http://www.washingtonpost.com/wp-dyn/content/video/2009/02/12/VI2009021203091.html

      Notice how ^^ Fauci laughs nervously while he explains
      that he has no clue what his scientists are doing,
      making it not too believable that he would be
      recognized as a leader, but then again, this is
      WaPo and the US News.

      Specifically, I would like you to note that Anthony
      Fauci owns a patent for a treatment of the immune
      suppression outcomes of diseases like LYMErix Disease
      (the disease caused by LYMErix or exposure to OspA):

      - - - - -
      "Illustrative of specific disease states in treatment of which the present invention can be applied are HIV infection and other diseases characterized by a decrease of T-cell immunity, for example, mycobacterial infections like tuberculosis and fungal infections such as cryptococcal disease."

      http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5%2C696%2C079.PN.&OS=PN%2F5%2C696%2C079&RS=PN%2F5%2C696%2C079 See More
      United States Patent: 5696079
      patft.uspto.gov
      "A method for activating a mammalian immune system entails a series of IL-2 administrations that are effected intermittently over an extended period. Each administration of IL-2 is sufficient to allow spontaneous DNA synthesis in peripheral blood or lymph node cells of the patient to ..."

      - - - - - -

      Meanwhile, there is a new campaign on by the NIH to
      hook up with BigPharma to resuscitate dead near-drugs, but
      still no one mentions publically what either Lyme Disease or
      LYMErix Disease actually is, ***so where would we even start to
      treat these outcomes?***

      I have been asking the NIH, CDC, NIAID, Fauci's office,
      IDSociety.org, and Yale over and over again for the
      past 2 months, if anyone could tell us what this
      antigen is, OspA. 

      No answer. 

      Only, now, a cowardly threat by Francis Collins, the
      fake Catholic.

      *WE* know what OspA is, because its structure
      was published in a non-PubMed-linked Korean
      Chemistry journal (Mass-Spec) and more recently
      by the Japanese (NMR).

      But the NIH cannot tell us what it is.  They cannot
      publically state what OspA is.  Either they don't
      know or they are afraid to admit the truth.

      We believe the latter to be a big possibility - they're
      all cowards - because Francis Collins, the fake-Catholic
      threatened me with "calling the police" if I called
      his office again to report that none of the people who
      work for him can tell me what OspA is.


      That kind of behavior is just plain *trashy.*  The NIH
      and CDC said OspA was a vaccine.  But they're going
      to throw me in jail for asking what it is?

      This is "Leadership?"

      So, we would like you, Mr Harvard Business School
      and Mormon who "asks the right questions" Mr. Christensen 
      to pick up the phone and call Francis Collins and Anthony
      Fauci and ask on our behalf for an answer to the OspA
      question.

      Thank you.

      Here is Francis Collins' phone number: 301-496-2433 

      Kathleen M. Dickson
      former Pfizer Analytical Methods
      Development and Validation chemist

       

      --------------------------------

      Once the NIH/CDC publically state what OspA is, that is the end of all "Lyme Disease" guidelines and diagnostic schemas.

      The Dearborn "case definition" was used to qualify the outcomes of the OspA vaccines. 

      Once we find out LYMErix or OspA could never have been a vaccine - because the NIH/CDC admit what it is - we will learn that the case definition used to qualify them must be false.

      And if Dearborn is false, so too, is Klempner and the "guidelines."

      Everything gets thrown out.  We treat based on the data and evidence available.

       

      Is this "Leadership" crap one big circle jerk or what?  They chronically reward and award each other for doing nothing and not being able to think.  Their personalities are like in the new Sasha Baron Cohen movie, The Dictator.
       

      Francis Collins:  "Ask again what OspA is, and I keel you."

       

       

       

       

       


       

      120516.htm

      1996; KOREANS : Characterization of Extremely Hydrophobic Immunostimulatory Lipoidal Peptides by Matrix Assisted Laser Desorption Ionization Mass Spectrometry

      Synthetic lipoidal peptides based on viral protein sequences have been prepared. These peptides contain an N-palmitoyl group at the N-terminal residue, which is a modified cysteine, containing a S-[2,3-bis(acyloxy)-(2-R,S)-propyl] moiety. When this residue (Pam3Cys) is at the N-terminus of a synthetic peptide, it acts as potent immunoadjuvant to enhance both IgM and IgG antibody responses to the attached peptide. Conventional analytical procedures (e.g., Edman degradation and amino acid analysis) are either not applicable due to the N-terminal modification, or do not provide confirmation of the intact structure. Chromatographic analysis is also hindered by the tendency of these lipoidal Pam3Cys peptides to form large aggregates, and in some cases to be permanently adsorbed on reversed phase columns. We have applied several mass spectrometric techniques, including fast atom bombardment (FAB), electrospray ionization (ESI) and matrix assisted laser desorption ionization (MALDI) to characterize the intact structures of a number of different Pam3Cys synthetic peptides. The MALDI-MS has been found to be the most sensitive for the analysis of the structure of Pam3Cys peptides. PDF


    Intracellular Lyme Grant intended to further the Intracellularity discovered by Mark Klempner in 1992:
     "Specifically, we propose to: (1) Characterize the invasion of borrelia burgdorferi into primary fibroblasts. The working hypothesis here is that B. burgdorferi exploits invasion as an additional mechanism to avoid host clearance. Our preliminary studies demonstrate that B. burgdorferi invasion is not dependent on host fibronectin, but does involve ?1 integrins other than... ?5?1. In this Aim we will identify the ??subunit that pairs with ?1 to promote invasion and will also evaluate how B. burgdorferi traffics within these cells; and (2) Determine if invasion is required for B. burgdorferi persistence in vivo. Our working hypothesis is that invasion contributes to persistence by providing an immunoprotected niche for B. burgdorferi. Since Src kinases are required for borrelial internalization in vitro, we will determine whether Src kinase inhibitors aler the infectivity potential of B. burgdorferi in vivo. In addition to standard cultivation and molecuar approaches, novel in vivo imaging will be employed to assess how the inhibitor affects colonization. The overall goal of these studies is to determine the extent in which an intracellula locale contributes to borrelial persistence."
    http://projectreporter.nih.gov/project_info_description.cfm?aid=8300386&icde=12284856

     

    An Admission that Lyme and LYMErix cause immunosuppression (Tufts, Linden Hu- published with Mark Klempner):
    "A better understanding of the workings of innate immunity is important for developing therapies for diseases such as Lyme disease where either an ineffective or an over-exuberant immune response causes the symptoms of illness." 
    http://projectreporter.nih.gov/project_info_description.cfm?aid=8228508&icde=12284856&ddparam&ddvalue&ddsub&cr=1&csb=FY&cs=DESC

     

    "Cause Known" Updates 120427: 
    Japanese also identify the structure of OspA; It appears to be Pam3Cys:
    A delicate interplay of structure, dynamics, and thermodynamics for function: a high pressure NMR study of outer surface protein A.
    http://www.sciencedirect.com/science/article/pii/S0006349511054075

    But the CDC says they do not recognize foreign research.  The CDC only apparently only recognizes their own foreign research, such as sending Allen Steere to Germany to falsify the diagnostic standard for Lyme