24 May 2012
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"Bacterial/Viral Coinfections";
TLR2 (fungi)Signaling Depletes IRAK1 and Inhibits Induction of Type 1 by TLR7/9 (viruses)-- -CV Harding, 2012 (More in the chart at the bottom of this homepage)
"Multiple Mechanisms of Immune Suppression by B Lymphocytes" (New and Trashes Yale and IDSA)
NIH's Treatment Recommendations for Chronic Active Epstein-Borreliosis, the chronic illness also induced by OspA vaccination or exposure to molds.
ELISA = arbitrary cutoff.
Disclaimer
1998, CIA Oilmen & Israelis plan to overthrow Saddam for the oil.
Bush/Gore Oil/War-(Oct,2000)
Bush's own explainer (Oct
2000) re:
Iraq Oil
INTERNATIONAL CRIMINAL COURT
The Hague
The Netherlands
29 JULY 2006
REPLY REGARDING THE UNITED STATES CENTERS FOR DISEASE CONTROL, et al, AND THEIR SCIENTIFIC FRAUD AS CONCERNS “LYME DISEASE”
The University of State of Connecticut (UCONN) experimented on Czech children with a vaccine (LYMErix) that they knew would do them no good, and was this only meant to be an experiment to determine how serious would be the vaccine injuries to these children.
In the United States we refer to this as being “human guinea pigs,” and why animal rights campaigners waste everyone’s time and cause all the ruckus that they do, availing the stupid FBI to be distracted with nonsense (which happens to be their preference, because 9/11 was a false flag operation and the favorite topic of the New Haven FBI is pornography, while they have this huge international scientific fraud crime being conducted from Yale, right across the street) while all this other deliberate harm to children occurs unchecked is beyond reasoning to someone like myself who has always worked in the medical field.
There is none of that kind (B31) of LYMErix OspA in Europe, and SmithKline and Yale and UCONN knew it at least 5 years pervious to this injury-experiment on Czech children. In the United States, this could be considered “assault,” since Yale had already proven that LYMErix did not prevent Lyme disease. Yale only proved that LYMErix made the spirochetes not only expand in ticks, but not express OspA- which is the very nature of a relapsing fever borreliosis.
There’s the proof. I gave this data to the local FBI and USDOJ but they all happen to be idiots, which was why I had to contact the ICC.
All Yale did was report the following report was Lyme was a relapsing fever borreliosis and that no vaccine would ever work, since that is the nature of the relapse.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=pubmed&details_term=7729870%5BUID%5D
Infect Immun. 1995 May;63(5):1658-62.
Selection of variant Borrelia burgdorferi isolates from mice immunized with outer surface protein A or B.
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8031, USA.
A nonclonal population of Borrelia burgdorferi N40 (passage 3) that survived protective immunity following challenge inoculation of outer surface protein (Osp) A- or B-hyperimmunized mice were characterized for the molecular basis of evasion of immunity. Two of six B. burgdorferi isolates, cultured from OspA-immunized mice, had antigenic diversity in the carboxyl terminus of OspA and did not bind to the protective OspA monoclonal antibody designated IXDII. However, OspA-immunized mice challenged with these variants were fully protected. Moreover, B. burgdorferi isolates with a point mutation in ospB, which results in a truncated OspB that does not bind to protective OspB monoclonal antibody 7E6C, were frequently enriched after infection of OspB-immunized mice. These studies suggest that the incomplete efficacy of an OspA- or OspB-based vaccine may be partly due to immunomediated in vivo selective pressure, resulting in the persistence of some spirochetes that do not bind to protective antibodies.
These organisms change their outer surface proteins constantly and people can be infected with multiple “strains” rendering the immune system “completely overwhelmed” (CDC’s Alan Barbour, now at the new CDC Level IV Bioweapons lab at UCAL Irvine) for two reasons:
1) too many new antigens
2) immune suppression and resultant seronegativity
The United States Centers for Disease Control knew in 1992 that OspA or any of these lipoproteins would not work as a vaccine, because they themselves conducted the experiment where they created a strain of borrelia spirochete that did not have the OspA-B plasmid in it, simply by “selecting” “variants” that don’t produce these OspA-B antibodies, by using OspA-B antibodies to “select” them, because that is what is meant by RELAPSING FEVER BORRELIOSIS.
Here is that report:
http://www.jem.org/cgi/reprint/176/3/799
This is what happens in a mammal (human), too.
Not only did the CDC report that there can never be a vaccine for Lyme in 1992, they simultaneously reported that the current CDC testing for Lyme is bogus, because just as there are varying strains and the “overwhelming of the immune system,” the CDC is aware that not everyone presents with Lyme arthritis due to their genetic background and this is what they mean by “MHC-restricted and MHC-non-restricted antibodies” in their patents with SmithKline in Europe.
http://v3.espacenet.com/textdes?DB=EPODOC&IDX=AU4392093&F=8&QPN=AU4392093
“Summary of the Invention [from the CDC staff’s patents]:
”In one aspect, the invention provides isolated B. burgdorferi antigens which are regulated and differentiated by growth of the B. burgdorferi in a tick vector. Novel antigens of the invention are listed below in Table I.
”Certain of these antigens are characterized as being B. burgdorferi B31 strain specific and major histocompatibility complex(MHC) nonrestricted. Certain other of these antigens are characterized as being MHCrestricted. Sera generated to these antigens (B31 MHC nonrestricted and B31 MHC restricted) are further characterized by the ability or lack of ability to react with B. burgdorferi JD-1 strain; the antigens themselves (B31 MHC nonrestricted and B31 MHC restricted) are further characterized by being homologous or heterologous with B. burgdorferi JD-1 strain antigens. The most preferred antigens of this invention, because of their ability to induce cross-strain immunity to B. burgdorferi in different animal haplotypes, are characterized by being B31 MHC nonrestricted, JD-1 crossreactive, and JD-1 nonrestricted.Other antigens are also useful in vaccine compositions and as diagnostics.”
In addition to this clear patent claim, CDC explained even more clearly why there can never be a vaccine for Lyme, and that their current testing for Lyme is bogus for the very same reason, Alan Barbour (CDC Epidemiological Intelligence Officer) published the explicit reason, in this report about ANTIGENIC VARIATION IN VECTOR-BORNE PATHOGENS:
Antigenic variation in vector-borne pathogens.
University of California Irvine, Irvine, California 92697-4025, USA. abarbour@uci.edu
Several pathogens of humans and domestic animals depend on hematophagous arthropods to transmit them from one vertebrate reservoir host to another and maintain them in an environment. These pathogens use antigenic variation to prolong their circulation in the blood and thus increase the likelihood of transmission. By convergent evolution, bacterial and protozoal vector-borne pathogens have acquired similar genetic mechanisms for successful antigenic variation. Borrelia spp. and Anaplasma marginale (among bacteria) and African trypanosomes, Plasmodium falciparum, and Babesia bovis (among parasites) are examples of pathogens using these mechanisms. Antigenic variation poses a challenge in the development of vaccines against vector-borne pathogens.
It clearly also poses a challenge for diagnosis. This means the CDC’s current bogus schema for the testing for Lyme or any other borreliosis is bogus, and the same is true for the EUCALB and the ALDF, the Department of Health and Human Services, and everyone else who is well-paid to be a USA-dot-gov-idiot.
The only valid testing for Lyme is in Borrelia specific flagellin antibody, in antibody testing, since there is so much flagellin, and in Yale’s own patent words, “THE VAST MAJORITY” of Lyme-infected people have band 41 or antiflagellin antibody. Do look that up. Yale does indeed make that claim in US patent 5,618,533. Here’s the link to the journal report that preceded the patent. You will find that this research was funded by:
http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=1894359
the National Institutes of Health. So, we clearly both have to A) pay for- and B) suffer- this FRAUD and abuse.
Why it is okay for CDC to spin Lyme and also stand to profit personally from patent licensure while simultaneously being in receipt of a paycheck that says DOT GOV on it, denying people early and adequate care, guaranteeing permanent disability not only for Americans but for the entire planet, rendering us (again) at your doorstep?
We think this is criminal, and an international crime of medical negligence and FRAUD, far bigger than the stem cells fraud. That Korean researcher never actually hurt a living soul. Lyme causes Lou Gehrigs’ Disease or Amyotropic Lateral Sclerosis, which is not only deadly but a horrible illness and death.
The Connecticut Department of Mental Health and Addiction Services and Yale University staff committed perjury under oath in America and said Lyme borreliosis is not a brain disease, when Department of Energy and Department of Defense staff at Brookhaven National Labs (Ray Dattwyler and Ben Luft at State University of New York, Stony Brook) stated in a 1994 US Food and Drug Administration meeting that Lyme spirochetes have invaded the brain in 2/3 of the cases of a Lyme rash (and scanned in below):
http://www.actionlyme.org/Dattwyler_Luft_Bb_DNA_in_CSF.htm
Borrelioses have always been known to be permanent brain infections, at least since World War II, and this fact was reported in the literature here in the USA by the US Uniformed Services Hospital staff in Bethesda, Maryland, and in Europe (Lancet, by WWII British Army physicians and Wellcome Labs).
The EUCALB is a false or “front” non-profit which is identical to the ALDF.com bogus non-profit and they have identical disclaimers for “medical negligence” for any physicians who follow their recommendations, yet the physician organizations in the USA and the CDC state that they follow the ALDF/EUCALB recommendations for diagnosis and treatment of Lyme disease.
We really and truly do not have any intelligent life here in the UnItEd StAtEs of AmeЯIcA.
OspA was the (LYMErix) vaccine, but if a person has that antibody, they don’t have Lyme disease, according to Yale, the CDC, and UCONN, which is clearly FRAUD. If this vaccine was specific enough to prevent Lyme disease (100% specificity), then it is certainly specific enough to detect Lyme disease.
Not detecting Lyme disease early is the certain way to chronic disability because of the tissue damage from chronic illness and the immune dysregulation caused by these sticky triacyl lipopeptide fungal antigens which are the Outer Surface Proteins or Osps. These types of fungal antigens are also found in mycoplasmal (fungal infections). There has been no successful vaccine for tuberculosis, because when tried, these recombinant lipoprotein vaccines suppressed the immune system and resulted in an exacerbation of the infection.
Just like LYMErix did.
Also:
Eur J Immunol. 2003 Sep;33(9):2539-50.
Pathogenesis of Lyme neuroborreliosis: Borrelia burgdorferi lipoproteins induce both proliferation and apoptosis in rhesus monkey astrocytes.
Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, LA 70433, USA.
Brain invasion by Borrelia burgdorferi, the agent of Lyme disease, results in an inflammatory and neurodegenerative disorder called neuroborreliosis. In humans, neuroborreliosis has been correlated with enhanced concentration of glial fibrillary acidic protein in the cerebrospinal fluid, a sign of astrogliosis. Rhesus monkeys infected by us with B. burgdorferi showed evidence of astrogliosis, namely astrocyte proliferation and apoptosis. We formulated the hypothesis that astrogliosis could be caused by spirochetal lipoproteins. We established primary cultures of rhesus monkey astrocytes and stimulated the cells with recombinant lipidated outer surface protein A (L-OspA), a model B. burgdorferi lipoprotein, and tripalmitoyl-S-glyceryl-Cys-Ser-Lys(4)-OH (Pam(3)Cys), a synthetic lipopeptide that mimics the structure of the lipoprotein lipid moiety. L-OspA elicited not only astrocyte proliferation but also apoptosis, two features observed during astrogliosis. Astrocytes produced both IL-6 and TNF-alpha in response to L-OspA and Pam(3)Cys. Proliferation induced by L-OspA was diminished in the presence of an excess of anti-IL-6 antibody, and apoptosis induced by this lipoprotein was completely suppressed with anti-TNF-alpha antibody. Hence, IL-6 contributes to, and TNF-alpha determines, astrocyte proliferation and apoptosis, respectively, as elicited by lipoproteins. Our results provide proof of the principle that spirochetal lipoproteins could be key virulence factors in Lyme neuroborreliosis, and that astrogliosis might contribute to neuroborreliosis pathogenesis.
PMID: 12938230 [PubMed - indexed for MEDLINE]
Don’t we think it is the slightest bit interesting that OspA (LYMErix) caused a loss of brain-associated cells (apoptosis means auto-kill; the cells died)? This is the “vaccine,” after all.
These Pam3Cys triacyl lipopeptides have the effect of turning off the immune system, adhering to erythrocytes and producing irregularly formed lymphocytes, or result in immune incompetence, exacerbation of latent infections, Borreliosis infection results in the production of lymphocytes that are reminiscent of Epstein-Barr transformed cells, and they cause general weakness (Paul Duray’s chapter in “Lyme Disease, Molecular and Immunologic Approaches, Cold Spring Harbor 1992 conference, by Steve Schutzer)
All of these facts are known by the members of the ALDF.com and EUCALB, because I am reciting their own research results.
Considering the numbers of people here and in Eurasia who are disabled from borrelioses, and who will in the future become disabled from borrelioses- and in particular due to the fact of the fraud in testing perpetrated by Yale, UCONN, the CDC, the EUCALB and the ALDF.com, this is certainly a crime against humanity, because as previously reported to the UN, in April 2003, citing the Declaration of Human Rights
http://www.actionlyme.org/UN_PETITION.htm
Article 2
- Each State Party to the present Covenant undertakes to take steps, individually and through international assistance and co_operation, especially economic and technical, to the maximum of its available resources, with a view to achieving progressively the full realization of the rights recognized in the present Covenant by all appropriate means, including particularly the adoption of legislative measures.
What we now know is that in any of these crazy reports by Yale wherein they now say Lyme is a nothing-disease with no consequences, we know that is because they are not using their validated and accurate Lyme borreliosis flagellin antibody test, which is about 95% accurate according to Yale’s own validation, and the criteria for the validation of a bioanalytical method per the US FDA rules.
- - -
In it fact may be true that SmithKline is more of your (ICC-Europe) problem than the American’s FDA, since SmithKline is a British company, although Yale owns the patent for LYMErix. SmithKline manufactured it.
Imagine what it is like living here in NUTCASE-ville, Corrupticut, with all these Yalie psychopathic idiots running around, like “president” George W. Bush, Prescott Bush, and Jonathan Bush - who is infamous for The Riggs Bank scandal, since that happened while Uncle Jonathan Bush Warbucks was running that CIA Spook Bank, and who laundered money for the dictator Pinochet, as well as holding money for about 50 Saudi families, allegedly including funding the 9/11 hijackers, lending credibility to the argument that 9/11 was a controlled demolition. Simultaneously, George W. Bush’s brother Marvin Bush’s company was in charge of “security” for the World Trade Center- the very-heavily-insured-against-terrorists-attacks-World-Trade-Center, one building of which collapsed due to sheer fright (WTC building 7). I guess the construction engineers who designed the WTC hadn’t planned on these poor WTC buildings being “Shocked and Awed” to death.
Do help us out and take it upon yourselves to work up the specific violation, since you know the situation is hopeless here in BULLSHIT-DEMOCRACY-LAND. Look how many people we killed in Iraq and then the Neocons suddenly realized Chalabi was an Iranian spy, and we DIDN’T get to steal their oil to pay ourselves for blasting the shit out their people and their country.
Do you really think America is a place from which we DON’T need to seek asylum or other assistance? A Connecticut asylum-seeker named Ritt Goldstein is quite famous for being harassed by the psycho NAZI jack-booted psychopathic cops here in Corrupticut.. Google him. He’s hiding in Europe somewhere, still. And it was from CONNECTICUT that he escaped with his life. We suck.
Thank you.
Kathleen M. Dickson
23 Garden Street
Pawcatuck, CT 06379
ActionLyme.org
RAY DATTWYLER AT THE JUNE 1994 FDA MEETING:
GRANTS ACKNOWLEDGED:
YALE'S EROL FIKRIG EXPLAINS WHY DURLAND FISH IS INSANE- YOU CAN'T VACCINATE WILD MICE WITH LYMERIX:
